- 专利标题： Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
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申请号： US17892496申请日： 2022-08-22
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公开(公告)号： US11964026B2公开(公告)日： 2024-04-23
- 发明人: Antonio Eric Barberio , Santiago Correa Echavarria , Mariane Bandeira Melo , Talar Tokatlian , Erik Christopher Dreaden , Paula T. Hammond , Darrell J. Irvine
- 申请人： Massachusetts Institute of Technology
- 申请人地址： US MA Cambridge
- 专利权人： Massachusetts Institute of Technology
- 当前专利权人： Massachusetts Institute of Technology
- 当前专利权人地址： US MA Cambridge
- 代理机构： Foley Hoag LLP
- 代理商 Alexander Akhiezer; Lawrence P. Tardibono
- 主分类号： A61K47/54
- IPC分类号： A61K47/54 ; A61K9/00 ; A61K9/127 ; A61K38/20 ; A61K47/69 ; A61P35/00
摘要：
Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.
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