- 专利标题： Artificially-manipulated neovascularization regulatory system
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申请号： US17236660申请日： 2021-04-21
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公开(公告)号： US11999952B2公开(公告)日： 2024-06-04
- 发明人: Jeong Hun Kim , Sung Wook Park , Seokjoong Kim , Dong Woo Song
- 申请人： TOOLGEN INCORPORATED , SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , SEOUL NATIONAL UNIVERSITY HOSPITAL
- 申请人地址： KR Seoul
- 专利权人： TOOLGEN INCORPORATED,SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION,SEOUL NATIONAL UNIVERSITY HOSPITAL,INSTITUTE FOR BASIC SCIENCE
- 当前专利权人： TOOLGEN INCORPORATED,SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION,SEOUL NATIONAL UNIVERSITY HOSPITAL,INSTITUTE FOR BASIC SCIENCE
- 当前专利权人地址： KR Seoul; KR Seoul; KR Seoul; KR Daejeon
- 代理机构： Harness, Dickey & Pierce, P.L.C.
- 主分类号： C12N15/00
- IPC分类号： C12N15/00 ; A61K9/00 ; A61K38/46 ; A61K48/00 ; C07K14/47 ; C07K14/515 ; C07K14/52 ; C12N9/22 ; C12N15/11 ; C12N15/113 ; C12N15/86
摘要：
The present invention relates to an artificially manipulated neovascularization-associated factor for regulating neovascularization and a use thereof. More particularly, the present invention relates to a system for artificially regulating neovascularization, which includes an artificially manipulated neovascularization-associated factor for regulating neovascularization and/or a composition for artificially manipulating the neovascularization-associated factor. In a specific aspect, a neovascularization regulatory system including a neovascularization-associated factor such as artificially manipulated VEGFA, HIF1A, ANGPT2, EPAS1, or ANGPTL4 and/or an expression product thereof is provided.
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