- 专利标题： Production of human milk oligosaccharides in microbial hosts with engineered import / export
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申请号： US17323737申请日： 2021-05-18
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公开(公告)号： US12037622B2公开(公告)日： 2024-07-16
- 发明人: Stefan Jennewein , Dirk Wartenberg
- 申请人： Chr. Hansen HMO GmbH
- 申请人地址： DE Rheinbreitbach
- 专利权人： Chr. Hansen HMO GmbH
- 当前专利权人： Chr. Hansen HMO GmbH
- 当前专利权人地址： DE Rheinbreitbach
- 优先权： EP 184968 2015.09.12
- 分案原申请号： US15758653
- 主分类号： C12P19/18
- IPC分类号： C12P19/18 ; C12N1/20 ; C12N9/10 ; C12N15/70
摘要：
The present invention relates to methods for the production of oligosaccharides in genetically modified bacterial host cells, as well as to the genetically modified host cells used in the methods. The genetically modified host cell comprises at least one recombinant glycosyltransferase, and at least one nucleic acid sequence coding for a protein enabling the export of the oligosaccharide.
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