- 专利标题： Polypeptides binding to human complement C5
-
申请号： US17479101申请日： 2021-09-20
-
公开(公告)号： US12083160B2公开(公告)日： 2024-09-10
- 发明人: Charlotta Berghard , Magnus Berglund , Patrik Strömberg , Malin Lindborg , Elin Gunneriusson , Joachim Feldwisch
- 申请人： IPC Research, LLC
- 申请人地址： US DE Wilmington
- 专利权人： IPC Research, LLC
- 当前专利权人： IPC Research, LLC
- 当前专利权人地址： US DE Wilmington
- 代理机构： Grimes & Yvon LLP
- 优先权： SE 501458 2012.02.20
- 主分类号： C07K14/00
- IPC分类号： C07K14/00 ; A61K38/16 ; A61K47/64 ; A61K47/68 ; C07K14/195 ; C07K14/315 ; C07K14/47 ; C07K19/00 ; A61K38/00
摘要：
The present invention relates to C5 binding polypeptides, comprising a C5 binding motif, BM, which motif consists of an amino acid sequence selected from i) EX2X3X4A X6 X7EID X11LPNL X16X17X18QW X21AFIX25X26LX28D, and ii) an amino acid sequence which has at least 86% identity to the sequence defined in i), wherein the polypeptide binds to C5. The present invention moreover relates to C5 binding polypeptides for use in therapy, such as for use in treatment of a C5 related condition, and to methods of treatment.
公开/授权文献
- US20210401930A1 POLYPEPTIDES BINDING TO HUMAN COMPLEMENT C5 公开/授权日：2021-12-30
信息查询
