Invention Grant
- Patent Title: Modulating human Cas9-specific host immune response
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Application No.: US17546810Application Date: 2021-12-09
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Publication No.: US12084691B2Publication Date: 2024-09-10
- Inventor: Radwa Ewaisha , Samira Kiani , Shayesteh Roshdi Ferdosi , Karen Anderson , Farzaneh Moghadam , Sri Krishna , Mo Reza Ebrahimkhani
- Applicant: Arizona Board of Regents on behalf of Arizona State University
- Applicant Address: US AZ Scottsdale
- Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
- Current Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
- Current Assignee Address: US AZ Scottsdale
- Agency: Quarles & Brady, LLP
- The original application number of the division: US16632782
- Main IPC: C12N9/22
- IPC: C12N9/22 ; A61K48/00 ; G01N33/573
Abstract:
Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-based genetic modulation.
Public/Granted literature
- US20220162574A1 Modulating Human Cas9-Specific Host Immune Response Public/Granted day:2022-05-26
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