- 专利标题: Bispecific anti-CCL2 antibodies
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申请号: US18509252申请日: 2023-11-14
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公开(公告)号: US12103967B2公开(公告)日: 2024-10-01
- 发明人: Jens Fischer , Guy Georges , Anton Jochner , Gregor Jordan , Hubert Kettenberger , Joerg Moelleken , Tilman Schlothauer , Georg Tiefenthaler , Valeria Runza , Meher Majety , Martin Schaefer , Maria Viert , Shu Feng , Wei Shiong Adrian Ho , Siok Wan Gan , Runyi Adeline Lam , Michael Gertz
- 申请人: Hoffmann-La Roche Inc.
- 申请人地址: US NJ Little Falls
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: US NJ Little Falls
- 优先权: EP 217665 2019.12.18
- 分案原申请号: US18335941 2023.06.15
- 主分类号: C07K16/46
- IPC分类号: C07K16/46 ; A61K39/385 ; C07K16/24 ; C12N5/00 ; C12N15/09 ; A61K39/00 ; C12N5/07 ; C12N15/63
摘要:
The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.
公开/授权文献
- US20240117029A1 BISPECIFIC ANTI-CCL2 ANTIBODIES 公开/授权日:2024-04-11
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