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公开(公告)号:US11739142B2
公开(公告)日:2023-08-29
申请号:US17123465
申请日:2020-12-16
发明人: Jens Fischer , Guy Georges , Anton Jochner , Gregor Jordan , Hubert Kettenberger , Joerg Moelleken , Tilman Schlothauer , Georg Tiefenthaler , Valeria Runza , Meher Majety , Martin Schaefer , Maria Viert , Shu Feng , Wei Shiong Adrian Ho , Siok Wan Gan , Runyi Adeline Lam , Michael Gertz
CPC分类号: C07K16/24 , A61K2039/505 , C07K2317/31 , C07K2317/565
摘要: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.
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公开(公告)号:US12103967B2
公开(公告)日:2024-10-01
申请号:US18509252
申请日:2023-11-14
发明人: Jens Fischer , Guy Georges , Anton Jochner , Gregor Jordan , Hubert Kettenberger , Joerg Moelleken , Tilman Schlothauer , Georg Tiefenthaler , Valeria Runza , Meher Majety , Martin Schaefer , Maria Viert , Shu Feng , Wei Shiong Adrian Ho , Siok Wan Gan , Runyi Adeline Lam , Michael Gertz
IPC分类号: C07K16/46 , A61K39/385 , C07K16/24 , C12N5/00 , C12N15/09 , A61K39/00 , C12N5/07 , C12N15/63
CPC分类号: C07K16/24 , A61K39/385 , A61K2039/505 , C07K16/46 , C07K2317/31 , C07K2317/565 , C12N5/06 , C12N15/09 , C12N15/63
摘要: The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases.
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