- 专利标题: Linker containing arylnitro, antibody-drug conjugate containing linker and use of linker
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申请号: US17271882申请日: 2019-08-28
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公开(公告)号: US12115226B2公开(公告)日: 2024-10-15
- 发明人: Xinbo Zhou , Yanming Wang , Song Li , Wu Zhong , Shiyong Fan , Dian Xiao , Junhai Xiao , Zhibing Zheng , Xingzhou Li , Yunde Xie , Ruiyuan Cao , Xiaokui Wang
- 申请人: Academy of Military Medical Sciences
- 申请人地址: CN Beijing
- 专利权人: Academy of Military Medical Sciences
- 当前专利权人: Academy of Military Medical Sciences
- 当前专利权人地址: CN Beijing
- 代理机构: Honigman LLP
- 优先权: CN 1811002559.2 2018.08.30
- 国际申请: PCT/CN2019/103053 2019.08.28
- 国际公布: WO2020/043129A 2020.03.05
- 进入国家日期: 2021-02-26
- 主分类号: A61K47/68
- IPC分类号: A61K47/68 ; A61K31/337 ; A61K31/4745 ; A61K31/537 ; A61K31/5517 ; A61K31/704 ; A61K38/07 ; A61K47/54 ; A61P35/00 ; C07C237/04 ; C07D207/452 ; C07D233/94 ; C07D307/71 ; C07D333/44 ; C07D403/04 ; C07D405/12 ; C07D409/12
摘要:
The present application relates to a linker containing arylnitro, an antibody-drug conjugate the linker and use of the linker, as well as a pharmaceutical composition comprising the antibody-drug conjugate and use of the antibody-drug conjugate for treatment and/or prevention of a disease
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