- 专利标题： LC/MS adduct mitigation by vapor deposition coated surfaces
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申请号： US18216064申请日： 2023-06-29
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公开(公告)号： US12117427B2公开(公告)日： 2024-10-15
- 发明人: Kerri M. Smith , Paul Rainville
- 申请人： Waters Technologies Corporation
- 申请人地址： US MA Milford
- 专利权人： Waters Technologies Corporation
- 当前专利权人： Waters Technologies Corporation
- 当前专利权人地址： US MA Milford
- 代理机构： WOMBLE BOND DICKINSON (US) LLP
- 代理商 Deborah M. Vernon; Mark R. Deluca
- 主分类号： G01N30/72
- IPC分类号： G01N30/72 ; C23C14/04 ; C23C14/12 ; C23C14/46 ; G01N30/02
摘要：
The present disclosure discusses a method of separating a sample (e.g., small organic acid metabolite) including coating a flow path of a chromatographic system. The coating along the flow path is vapor deposited and prevents or severely decreases metal interactions between the metallic chromatographic system and the sample.
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