Invention Grant
- Patent Title: Method for producing a vadadustat intermediate
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Application No.: US17605408Application Date: 2020-03-05
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Publication No.: US12134600B2Publication Date: 2024-11-05
- Inventor: Koji Machida , Hiroaki Yasukouchi , Akira Nishiyama
- Applicant: KANEKA CORPORATION
- Applicant Address: JP Osaka
- Assignee: KANEKA CORPORATION
- Current Assignee: KANEKA CORPORATION
- Current Assignee Address: JP Osaka
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2019-086759 20190426
- International Application: PCT/JP2020/009453 WO 20200305
- International Announcement: WO2020/217733 WO 20201029
- Main IPC: C07D213/81
- IPC: C07D213/81

Abstract:
A method for producing a first vadadustat intermediate represented by the following formula (3) comprising reacting a compound represented by the following formula (1) with glycine or a glycine derivative represented by the following formula (2) or a salt of the glycine or the glycine derivative in the presence of carbon monoxide. The method produces a vadadustat intermediate through a clean reaction with high atom conversion efficiency.
Public/Granted literature
- US20220204451A1 METHOD FOR PRODUCING A VADADUSTAT INTERMEDIATE Public/Granted day:2022-06-30
Information query
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