A smart cloth includes a cloth body, a control body, actuation air-permeable components, temperature sensing components, and a health-monitoring device. The health-monitoring device includes a bio-sensing module, a blood glucose sensor, a blood pressure measurement module, and a gas bag. The temperature information of the wearer is detected by the temperature sensing components and outputted to the microprocessor of the control body, so that the microprocessor controls the actuation air-permeable components to perform the gas-guiding operation to adjust an apparent temperature of the wearer for providing wearing comfortableness. The bio-sensing module, the blood glucose sensing module, and the blood pressure measurement module detect and provide the detection data information for the wearer anytime and in real-time to provide health-related information to the wearer. Furthermore, the smart cloth may include a gas detection module, allowing the wearer to obtain gas data information anytime and anywhere for alerting and notifying the wearer.