Methods, apparatus, systems, and articles of manufacture to control an aggressiveness of display panel power savings are disclosed. An example apparatus include a display panel, a display controller to adjust an image to be displayed by the display panel, and a power savings controller to access an image provided to the display controller, execute a machine learning model using the image as an input to generate an aggressiveness value, and provide the aggressiveness value to the display controller, the display controller to adjust the image based on the aggressiveness value.