Invention Application
- Patent Title: Enteric formulations of proanthocyanidin polymer antidiarrheal compositions
- Patent Title (中): 原花色素聚合物抗腹泻组合物的肠溶制剂
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Application No.: US10919969Application Date: 2004-08-17
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Publication No.: US20050019389A1Publication Date: 2005-01-27
- Inventor: Edward Rozhon , Atul Khandwala , Akram Sabouni , Gul Balwani , Jody Chan , David Sesin
- Applicant: Edward Rozhon , Atul Khandwala , Akram Sabouni , Gul Balwani , Jody Chan , David Sesin
- Assignee: PS Pharmaceutical, Inc.
- Current Assignee: PS Pharmaceutical, Inc.
- Main IPC: C07D311/62
- IPC: C07D311/62 ; A61K9/10 ; A61K9/28 ; A61K9/32 ; A61K9/50 ; A61K9/54 ; A61K9/58 ; A61K31/352 ; A61K31/353 ; A61K31/765 ; A61K36/18 ; A61K47/32 ; A61P1/12 ; A61P31/04 ; A61K35/78 ; A61K31/7048 ; A61K9/48
Abstract:
Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer composition which has been isolated from a Croton spp. or a Calophyllum spp. In particular, the invention relates to a formulation of a proanthocyanidin polymer composition which protects the composition from the effects of stomach acid after oral administration, particularly to those formulations which are enteric coated. The invention also relates to methods of producing a directly compressible proanthocyanidin polymer composition, as well as compositions containing the directly compressible proanthocyanidin polymer composition.
Public/Granted literature
- US07323195B2 Enteric formulations of proanthocyanidin polymer antidiarrheal compositions Public/Granted day:2008-01-29
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