发明申请
- 专利标题: Core structure of gp41 from the HIV envelope glycoprotein
- 专利标题(中): 来自HIV包膜糖蛋白的gp41的核心结构
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申请号: US10680853申请日: 2003-10-07
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公开(公告)号: US20050053917A1公开(公告)日: 2005-03-10
- 发明人: David Chan , Deborah Fass , Min Lu , James Berger , Peter Kim
- 申请人: David Chan , Deborah Fass , Min Lu , James Berger , Peter Kim
- 申请人地址: US MA Cambridge
- 专利权人: Whitehead Institute for Biomedical Research
- 当前专利权人: Whitehead Institute for Biomedical Research
- 当前专利权人地址: US MA Cambridge
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/16 ; C12Q1/70 ; A61K38/06 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00
摘要:
Described are the crystal structure of the α-helical domain of the gp41 component of HIV-1 envelope glycoprotein which represents the core of fusion-active gp41, methods of identifying and designing drugs which inhibit gp41 function and drugs which do so.
公开/授权文献
- US07402396B2 Core structure of gp41 from the HIV envelope glycoprotein 公开/授权日:2008-07-22
信息查询
IPC分类: