发明申请
US20050059714A1 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
有权
糖皮质激素模拟物,其制备方法,药物组合物及其用途
- 专利标题: Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
- 专利标题(中): 糖皮质激素模拟物,其制备方法,药物组合物及其用途
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申请号: US10944615申请日: 2004-09-17
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公开(公告)号: US20050059714A1公开(公告)日: 2005-03-17
- 发明人: Rajashehar Betageri , Thomas Gilmore , Christian Hanke Harcken , Daniel Kuzmich , Hossein Razavi , Doris Riether , David Thomson , Ji Wang
- 申请人: Rajashehar Betageri , Thomas Gilmore , Christian Hanke Harcken , Daniel Kuzmich , Hossein Razavi , Doris Riether , David Thomson , Ji Wang
- 申请人地址: US CT Ridgefield 06877-0368
- 专利权人: Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人: Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人地址: US CT Ridgefield 06877-0368
- 主分类号: A61K31/343
- IPC分类号: A61K31/343 ; A61K31/404 ; A61K31/405 ; A61K31/4184 ; A61K31/423 ; A61K31/437 ; A61K31/44 ; A61K31/4402 ; A61K31/4439 ; A61P1/00 ; A61P1/16 ; A61P3/04 ; A61P3/10 ; A61P5/00 ; A61P9/00 ; A61P9/10 ; A61P9/12 ; A61P17/00 ; A61P19/02 ; A61P25/00 ; A61P25/04 ; A61P27/02 ; A61P27/06 ; A61P27/16 ; A61P29/00 ; A61P35/00 ; A61P37/06 ; A61P37/08 ; C07C49/255 ; C07C49/577 ; C07D209/12 ; C07D209/30 ; C07D213/30 ; C07D213/61 ; C07D215/14 ; C07D217/16 ; C07D231/12 ; C07D233/54 ; C07D235/12 ; C07D237/08 ; C07D239/26 ; C07D241/12 ; C07D261/18 ; C07D263/32 ; C07D263/56 ; C07D277/24 ; C07D277/64 ; C07D307/80 ; C07D333/16 ; C07D401/06 ; C07D405/06 ; C07D471/04 ; C07D213/26 ; A61K31/138 ; A61K31/195 ; A61K31/277
摘要:
Compounds of Formula (IA) and Formula (IB) wherein R1, R2, R3, R4, R5, and R6 are as defined herein for Formula (IA) or Formula (IB), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
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