发明申请
- 专利标题： Methods for diagnosing cancer and determining a susceptibility for developing cancer
- 专利标题（中）： 诊断癌症和确定癌症易感性的方法
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申请号： US10364515申请日： 2003-02-12
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公开(公告)号： US20050074755A1公开(公告)日： 2005-04-07
- 发明人: Ying-Fei Wei
- 申请人： Ying-Fei Wei
- 申请人地址： US MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： US MD Rockville
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; A61K38/00 ; A61K48/00 ; A61P35/00 ; C07H21/02 ; C07H21/04 ; C07K14/47 ; C07K16/30 ; C12N9/22 ; C12N9/24 ; C12N15/00 ; C12N15/09 ; C12P21/02 ; C12P21/08 ; C12R1/19 ; C12R1/91 ; C12Q1/68 ; C12N5/06
摘要：
A human mutY polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for preventing and/or treating diseases associated with a mutation in this gene. Diagnostic assays for identifying mutations in nucleic acid sequence endcoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example, cancer, area also disclosed.
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