发明申请
- 专利标题: Glucose transport mutants for production of biomaterial
- 专利标题(中): 用于生物材料生产的葡萄糖转运突变体
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申请号: US10728337申请日: 2003-12-03
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公开(公告)号: US20050079617A1公开(公告)日: 2005-04-14
- 发明人: Marguerite Cervin , Philippe Soucaille , Fernando Valle , Gregory Whited
- 申请人: Marguerite Cervin , Philippe Soucaille , Fernando Valle , Gregory Whited
- 优先权: WOPCT/US03/31544 20031003
- 主分类号: C12N1/20
- IPC分类号: C12N1/20 ; C12N15/70 ; C12N15/74
摘要:
A method is disclosed for restoring a Glu+ phenotype to a PTS−/Glu− bacterial cell which was originally capable of utilizing a phosphotransferase transport system (PTS) for carbohydrate transport. Bacterial cells comprising the Glu+ phenotype have modified endogenous chromosomal regulatory regions which are operably linked to polynucleotides encoding galactose permeases and glucokinases.
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