- 专利标题： Inhibitors of cathepsin S
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申请号： US10970344申请日： 2004-10-20
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公开(公告)号： US20050130959A1公开(公告)日： 2005-06-16
- 发明人: Hong Liu , Phillip Alper , Daniel Mutnick , Donald Karanewsky
- 申请人： Hong Liu , Phillip Alper , Daniel Mutnick , Donald Karanewsky
- 申请人地址： BM Hamilton
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： BM Hamilton
- 主分类号： A61K
- IPC分类号： A61K20060101 ; A61K31/34 ; A61K31/4025 ; A61K31/452 ; A61K31/496 ; A61K31/5375 ; A61K31/5377 ; A61K31/541 ; C07D307/04 ; C07D307/33 ; C07D405/12 ; C07D407/12 ; C07D413/02 ; C07D413/12 ; C07D417/02 ; C07D45/02
摘要：
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
公开/授权文献
- US07297714B2 Inhibitors of cathepsin S 公开/授权日：2007-11-20
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