发明申请
US20050148601A1 Neurokinin-3 receptor modulators: diaryl imidazole derivatives
审中-公开
神经激肽-3受体调节剂:二芳基咪唑衍生物
- 专利标题: Neurokinin-3 receptor modulators: diaryl imidazole derivatives
- 专利标题(中): 神经激肽-3受体调节剂:二芳基咪唑衍生物
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申请号: US11007652申请日: 2004-12-07
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公开(公告)号: US20050148601A1公开(公告)日: 2005-07-07
- 发明人: George Maynard , Stanislaw Rachwal , Wallace Pringle , Jun Yuan , Linghong Xie , Yuelian Xu , Bingsong Han
- 申请人: George Maynard , Stanislaw Rachwal , Wallace Pringle , Jun Yuan , Linghong Xie , Yuelian Xu , Bingsong Han
- 主分类号: A61K31/4178
- IPC分类号: A61K31/4178 ; A61K31/427 ; A61K31/4439 ; A61K31/498 ; A61K31/506 ; A61K31/538 ; C07D233/54 ; C07D401/04 ; C07D403/04 ; C07D405/04 ; C07D409/12 ; C07D413/02 ; C07D413/04 ; C07D417/02 ; C07D417/04 ; C07D43/02
摘要:
The invention relates to compounds of general Formula I: wherein the variables are as defined herein. Also provided are pharmaceutical compositions comprising such compounds, and methods for treating patients suffering from a disorder responsive to neurokinin-3 receptor modulation. NK-3 receptor modulators provided herein are also useful as probes for the localization of NK-3 receptors.
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