发明申请
- 专利标题： Substituted arylamine derivatives and methods of use
- 专利标题（中）： 取代的芳基胺衍生物和使用方法
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申请号： US10996035申请日： 2004-11-22
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公开(公告)号： US20050153960A1公开(公告)日： 2005-07-14
- 发明人: Daniel Elbaum , Benny Askew , Shon Booker , Julie Germain , Gregory Habgood , Michael Handley , Tae-Seong Kim , Aiwen Li , Nobuko Nishimura , Vinod Patel , Chester Yuan , Joseph Kim , Guolin Cai , Guoqing Chen , Michael Croghan , Lucian Di Pietro , Celia Dominguez , Qi Huang , Leon Smith , Andrew Tasker , Ning Xi , Shimin Xu
- 申请人： Daniel Elbaum , Benny Askew , Shon Booker , Julie Germain , Gregory Habgood , Michael Handley , Tae-Seong Kim , Aiwen Li , Nobuko Nishimura , Vinod Patel , Chester Yuan , Joseph Kim , Guolin Cai , Guoqing Chen , Michael Croghan , Lucian Di Pietro , Celia Dominguez , Qi Huang , Leon Smith , Andrew Tasker , Ning Xi , Shimin Xu
- 专利权人： Amgen Inc.
- 当前专利权人： Amgen Inc.
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61K31/4427 ; A61K31/443 ; A61K31/4436 ; A61K31/4439 ; A61K31/444 ; A61K31/4709 ; A61K31/4725 ; A61K31/496 ; A61K31/498 ; A61K31/501 ; A61K31/506 ; A61K31/517 ; A61K31/5377 ; A61K31/538 ; A61P1/04 ; A61P3/00 ; A61P3/04 ; A61P3/10 ; A61P9/00 ; A61P9/10 ; A61P11/00 ; A61P11/06 ; A61P15/00 ; A61P15/08 ; A61P17/00 ; A61P17/02 ; A61P17/06 ; A61P19/00 ; A61P19/02 ; A61P21/00 ; A61P25/28 ; A61P27/02 ; A61P27/06 ; A61P29/00 ; A61P31/12 ; A61P31/18 ; A61P31/22 ; A61P35/00 ; A61P35/02 ; A61P35/04 ; A61P37/02 ; A61P37/04 ; A61P37/08 ; A61P43/00 ; C07D213/81 ; C07D213/82 ; C07D237/04 ; C07D237/24 ; C07D401/12 ; C07D401/14 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D413/14 ; C07D417/12 ; C07D471/04 ; A61K31/4545 ; C07D413/02 ; C07D41/02
摘要：
Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
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