发明申请
- 专利标题: Nucleic acid ligands to the prostate specific membrane antigen
- 专利标题(中): 核酸配体对前列腺特异性膜抗原
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申请号: US11029949申请日: 2005-01-04
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公开(公告)号: US20050158780A1公开(公告)日: 2005-07-21
- 发明人: Shawn Lupold , Yun Lin , Brian Hicke , Donald Coffey
- 申请人: Shawn Lupold , Yun Lin , Brian Hicke , Donald Coffey
- 申请人地址: US CA Foster City
- 专利权人: GILEAD SCIENCES, INC.
- 当前专利权人: GILEAD SCIENCES, INC.
- 当前专利权人地址: US CA Foster City
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K47/48 ; A61K51/00 ; A61P35/00 ; C07K14/705 ; C07K17/02 ; C12N15/115 ; C12Q1/68 ; C07F5/00 ; C07H21/02
摘要:
Methods are provided for generating nucleic acid ligands of Prostate Specific Membrane Antigen (PSMA). The methods of the invention use the SELEX method for the isolation of nucleic acid ligands. The invention also includes nucleic acid ligands to PSMA, and methods and compositions for the treatment and diagnosis of disease using the nucleic acid ligands.
公开/授权文献
- US2676488A Quantitative flow indicator 公开/授权日:1954-04-27
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