发明申请
US20050164305A1 Diagnostics and therapeutics for diseases associated with n-formyl peptide receptor like 1 (fprl1)
审中-公开
与正甲酰基肽受体1（fprl1）相关的疾病的诊断和治疗
- 专利标题： Diagnostics and therapeutics for diseases associated with n-formyl peptide receptor like 1 (fprl1)
- 专利标题（中）： 与正甲酰基肽受体1（fprl1）相关的疾病的诊断和治疗
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申请号： US10509715申请日： 2003-03-21
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公开(公告)号： US20050164305A1公开(公告)日： 2005-07-28
- 发明人: Stefan Golz , Ulf Bruggemeier , Andreas Geerts
- 申请人： Stefan Golz , Ulf Bruggemeier , Andreas Geerts
- 申请人地址： DE Leverkusen 51368
- 专利权人： Bayer HealthCare AG
- 当前专利权人： Bayer HealthCare AG
- 当前专利权人地址： DE Leverkusen 51368
- 优先权： EP02007291.4 20020403
- 国际申请： PCT/EP03/02959 WO 20030321
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; A61K31/7088 ; A61K31/7105 ; A61K38/00 ; A61K38/46 ; A61K39/395 ; A61K45/00 ; A61K48/00 ; A61P7/00 ; A61P9/00 ; A61P11/00 ; A61P11/06 ; A61P13/00 ; A61P15/00 ; A61P25/02 ; A61P25/28 ; A61P29/00 ; C12N15/09 ; C12Q1/02 ; C12Q1/68 ; G01N33/15 ; G01N33/566 ; G01N33/68 ; G01N33/74 ; G01N33/53 ; A61K38/17 ; G01N33/567
摘要：
The invention provides a human FPRL1 which is associated with the hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD, asthma, genito-urological disorders and inflammation diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD, asthma, genito-urological disorders and inflammation diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of FPRL1 as well as pharmaceutical compositions comprising such compounds.
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