发明申请
US20050164973A1 1,2,4-Oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease
有权
1,2,4-恶二唑苯甲酸化合物及其用于无味抑制和治疗疾病的用途
- 专利标题： 1,2,4-Oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease
- 专利标题（中）： 1,2,4-恶二唑苯甲酸化合物及其用于无味抑制和治疗疾病的用途
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申请号： US11042652申请日： 2005-01-24
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公开(公告)号： US20050164973A1公开(公告)日： 2005-07-28
- 发明人: Gary Karp , Seongwoo Hwang , Guangming Chen , Neil Almstead
- 申请人： Gary Karp , Seongwoo Hwang , Guangming Chen , Neil Almstead
- 专利权人： PCT Therapeutics, Inc.
- 当前专利权人： PCT Therapeutics, Inc.
- 主分类号： A61K31/4245
- IPC分类号： A61K31/4245 ; C07D271/06 ; C07D271/12 ; C07D413/04 ; C07D413/10 ; A61K48/00 ; C12N15/85
摘要：
Novel 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising an 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease ameliorated by modulation of premature translation termination or nonsense-mediated mRNA decay, or ameliorating one or more symptoms associated therewith.