发明申请
US20050170330A1 Angiogensis models using nestin-expressing stem cells to image nascent blood vessels
失效
使用巢蛋白表达干细胞来形成新生血管的血管生成模型
- 专利标题： Angiogensis models using nestin-expressing stem cells to image nascent blood vessels
- 专利标题（中）： 使用巢蛋白表达干细胞来形成新生血管的血管生成模型
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申请号： US10977219申请日： 2004-10-28
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公开(公告)号： US20050170330A1公开(公告)日： 2005-08-04
- 发明人: Yasuyuki Amoh , Lingna Li , Meng Yang , Ping Jiang
- 申请人： Yasuyuki Amoh , Lingna Li , Meng Yang , Ping Jiang
- 申请人地址： US CA San Diego
- 专利权人： AntiCancer, Inc.
- 当前专利权人： AntiCancer, Inc.
- 当前专利权人地址： US CA San Diego
- 主分类号： A01K67/027
- IPC分类号： A01K67/027 ; A01N63/00 ; C12Q1/00 ; G01N33/50
摘要：
The disclosed invention relates to the observation that nestin expression is a marker for endothelial cell proliferation. Nestin expression is particularly useful as a marker for angiogenesis, particularly for tumor-related angiogenesis. Specifically, nestin serves as an excellent endothelium marker for brain tumors such as gliomas, hemangioblastomas, Schwannomas, medulloblastomas, and meningiomas. Accordingly, the disclosed invention relates to the use of this marker as a basis to model angiogenic activity.
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