发明申请
US20050176016A1 Beta-catenin oligonucleotide microchip and method for detecting beta-catenin mutations employing same
有权
β-连环蛋白寡核苷酸微芯片和使用其检测β-连环蛋白突变的方法
- 专利标题： Beta-catenin oligonucleotide microchip and method for detecting beta-catenin mutations employing same
- 专利标题（中）： β-连环蛋白寡核苷酸微芯片和使用其检测β-连环蛋白突变的方法
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申请号： US10659583申请日： 2003-09-09
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公开(公告)号： US20050176016A1公开(公告)日： 2005-08-11
- 发明人: Jae-Gahb Park , Il-Jin Kim , Hio-Chung Kang , Jae-Hyun Park
- 申请人： Jae-Gahb Park , Il-Jin Kim , Hio-Chung Kang , Jae-Hyun Park
- 优先权： KR2003-0000987 20030108
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C12M1/00 ; C12M1/34 ; C12N15/09 ; C12Q1/68 ; G01N33/574 ; G01N33/68 ; G01N37/00
摘要：
The present invention relates to a β-catenin oligonucleotide microchip for detecting mutation in the mutational hot spot regions of β-catenin gene, a manufacturing process thereof and a method for detecting the β-catenin mutation employing same, wherein specific oligonucleotides are selectively designed to detect various missense mutations and in-frame deletion at the mutational hot spots of β-catenin gene. The β-catenin oligo chip of the present invention can be used in studies to detect β-catenin mutations and unravel the signal transduction mechanism and tumorigenesis related to β-catenin gene.
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