发明申请
- 专利标题: Recombinant protein containing serum albumin multimer
- 专利标题(中): 含重组蛋白的血清白蛋白多聚体
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申请号: US11068502申请日: 2005-03-01
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公开(公告)号: US20050203020A1公开(公告)日: 2005-09-15
- 发明人: Masaki Otagiri , Yoshinori Kida , Naohisa Katayama , Toshiya Kai
- 申请人: Masaki Otagiri , Yoshinori Kida , Naohisa Katayama , Toshiya Kai
- 优先权: JP2004-058620 20040303
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K38/00 ; A61K38/38 ; A61K47/42 ; C07K14/765 ; C12P21/02 ; C07H21/04
摘要:
A recombinant protein is provided containing a serum albumin multimer wherein at least two genes encoding serum albumin are combined with each other by gene recombinant technology and incorporated into a host cell for the effective production of the protein. The gene encoding a human serum albumin multimer and the recombinant vector are also provided. The protein is used as a safe drug administration carrier that is capable of extending the half life of a drug in the blood without the risk of contamination of viruses and so on, as compared with a conventional drug administration carrier.
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