发明申请
US20050203092A1 4-Pyrimidinamine derivatives, pharmaceutical compositions and related methods
审中-公开
4-嘧啶胺衍生物，药物组合物和相关方法
- 专利标题： 4-Pyrimidinamine derivatives, pharmaceutical compositions and related methods
- 专利标题（中）： 4-嘧啶胺衍生物，药物组合物和相关方法
-
申请号： US10987562申请日： 2004-11-12
-
公开(公告)号： US20050203092A1公开(公告)日： 2005-09-15
- 发明人: Elfrida Benjamin , Frank Brown , Robert Zivin , Michael McMillan , Zhong Zhong , Allen Reitz , Tina Ross
- 申请人： Elfrida Benjamin , Frank Brown , Robert Zivin , Michael McMillan , Zhong Zhong , Allen Reitz , Tina Ross
- 主分类号： C07D239/12
- IPC分类号： C07D239/12 ; C07D239/42 ; C07D239/52 ; C07D401/12 ; C07D405/04 ; C07D409/04 ; C07D495/04 ; C07D413/02 ; A61K31/506 ; A61K31/5377 ; C07D43/02
摘要：
This invention provides novel neuroprotective 4-pyrimidineamine derivatives and neuroprotective pharmaceutical compositions comprising 4-pyrimidinamines. This invention also provides methods of using these compositions to prevent ischemic cell death, particularly neuronal cell death, and reduce the likelihood of neuronal cell death in a subject due to a traumatic event. Finally, this invention provides an apparatus for administering to a subject the instant pharmaceutical compositions.