Invention Application
- Patent Title: N-phenyl-(2r,5s) dimethylpiperadine derivative
- Patent Title (中): N-苯基 - （2r，5s）二甲基哌啶衍生物
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Application No.: US10521119Application Date: 2003-07-11
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Publication No.: US20050261303A1Publication Date: 2005-11-24
- Inventor: Nobuaki Taniguchi , Masakazu Imamura , Masahiko Hayakawa , Kenichi Kawaguchi , Takenori Kimura , Isao Kinoyama , Hiroyuki Kaizawa , Minoru Okada , Takashi Furutani
- Applicant: Nobuaki Taniguchi , Masakazu Imamura , Masahiko Hayakawa , Kenichi Kawaguchi , Takenori Kimura , Isao Kinoyama , Hiroyuki Kaizawa , Minoru Okada , Takashi Furutani
- Priority: JP2002-203690 20020712
- International Application: PCT/JP03/08860 WO 20030711
- Main IPC: A61P5/28
- IPC: A61P5/28 ; A61P13/08 ; A61P17/08 ; A61P17/14 ; A61P35/00 ; C07D213/75 ; C07D213/84 ; C07D239/42 ; C07D295/215 ; A61K31/496 ; A61K31/506 ; C07D43/02
Abstract:
The present invention relates to a novel N-phenyl-(2R,5S)dimethylpiperazine derivatives useful as antiandrogenic agent which exhibits a sufficient prostate gland reducing effect as compared with conventional compounds and are excellent in oral activity. The compound of the present application is useful in preventing or treating prostate cancer, benign prostatic hyperplasia, and the like. The present invention also provides a novel intermediate useful in producing the compound of the present invention.
Public/Granted literature
- US07297698B2 N-phenyl-(2R,5S) dimethylpiperazine derivative Public/Granted day:2007-11-20
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