发明申请
US20050272702A1 Coupling process for generating reactive boron-containing derivatives of N-substituted pyrrole-2-carbonitriles to produce biaryls
失效
用于产生N-取代的吡咯-2-碳腈的反应性含硼衍生物以产生联芳基的偶联方法
- 专利标题： Coupling process for generating reactive boron-containing derivatives of N-substituted pyrrole-2-carbonitriles to produce biaryls
- 专利标题（中）： 用于产生N-取代的吡咯-2-碳腈的反应性含硼衍生物以产生联芳基的偶联方法
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申请号： US11113794申请日： 2005-04-25
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公开(公告)号： US20050272702A1公开(公告)日： 2005-12-08
- 发明人: Bogdan Wilk , Arkadiy Rubezhov , Jean Helom
- 申请人： Bogdan Wilk , Arkadiy Rubezhov , Jean Helom
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 主分类号： A61K31/69
- IPC分类号： A61K31/69 ; C07D413/04 ; C07F5/02
摘要：
A convenient preparation of boron-containing compounds, borate salts, pyrrolecarbonitrile boron-containing compounds, N-substituted-pyrrole-2-carbonitrile boron-containing compounds, and derivatives thereof is provided. The present invention also provides for the use of these boron-containing compounds and derivatives thereof in coupling reactions to provide bi-aryl compounds.
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