发明申请
US20060110771A1 Proteins capable of binding to female sex hormones and process for producing the same
审中-公开
能够结合女性性激素的蛋白质及其制备方法
- 专利标题： Proteins capable of binding to female sex hormones and process for producing the same
- 专利标题（中）： 能够结合女性性激素的蛋白质及其制备方法
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申请号： US10506063申请日： 2003-02-28
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公开(公告)号： US20060110771A1公开(公告)日： 2006-05-25
- 发明人: Masanao Katagiri , Shigeru Fujimoto , Yasuhiro Goda
- 申请人： Masanao Katagiri , Shigeru Fujimoto , Yasuhiro Goda
- 优先权： JP2002-55669 20020301
- 国际申请： PCT/JP03/02311 WO 20030228
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07H21/04 ; C12P21/06 ; C07K14/72 ; C07J5/00
摘要：
The present invention provides a protein capable of binding to a female sex hormone, which protein is supplemented with useful properties for measuring, quantifying and concentrating female sex hormones, such as high sensitivity, low cross-reactivity, unlikelihood of being influenced by interfering substances, and unlikelihood of being influenced by solvents. Specifically, the present invention provides a recombinant protein prepared by obtaining various genes for various antibodies against female sex hormones, and modifying, by gene recombination technology, various properties of the original antibody, such as affinity, avidity, cross-reactivity, resistance for interfering substance on antigen-antibody reaction, resistance for interfering substance on enzymatic color developing reaction, resistance for solvent and the like.
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