Proteins capable of binding to female sex hormones and process for producing the same
    1.
    发明申请
    Proteins capable of binding to female sex hormones and process for producing the same 审中-公开
    能够结合女性性激素的蛋白质及其制备方法

    公开(公告)号:US20060110771A1

    公开(公告)日:2006-05-25

    申请号:US10506063

    申请日:2003-02-28

    摘要: The present invention provides a protein capable of binding to a female sex hormone, which protein is supplemented with useful properties for measuring, quantifying and concentrating female sex hormones, such as high sensitivity, low cross-reactivity, unlikelihood of being influenced by interfering substances, and unlikelihood of being influenced by solvents. Specifically, the present invention provides a recombinant protein prepared by obtaining various genes for various antibodies against female sex hormones, and modifying, by gene recombination technology, various properties of the original antibody, such as affinity, avidity, cross-reactivity, resistance for interfering substance on antigen-antibody reaction, resistance for interfering substance on enzymatic color developing reaction, resistance for solvent and the like.

    摘要翻译: 本发明提供能够结合雌性激素的蛋白质,该蛋白质补充有用于测量,定量和浓缩女性性激素的有用性质,例如高灵敏度,低交叉反应性,受干扰物质影响的不可靠性, 并且不受溶剂影响。 具体地说,本发明提供了通过获得针对女性性激素的各种抗体的各种基因而制备的重组蛋白质,并且通过基因重组技术修饰原始抗体的各种性质,例如亲和力,亲合力,交叉反应性,抗干扰性 抗原抗体反应的物质,干燥物质对酶显色反应的抵抗性,溶剂性等。