发明申请
US20060140933A1 Compositions and methods for treating rage-associated disorders
审中-公开
用于治疗愤怒相关疾病的组合物和方法
- 专利标题： Compositions and methods for treating rage-associated disorders
- 专利标题（中）： 用于治疗愤怒相关疾病的组合物和方法
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申请号： US10643589申请日： 2003-08-18
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公开(公告)号： US20060140933A1公开(公告)日： 2006-06-29
- 发明人: Debra Pittman , Brian Clancy , Glenn Larsen , William Trepicchio , Fionula Brennan , Marc Feldmann , Brian John Foxwell , Jeffrey Feldman
- 申请人： Debra Pittman , Brian Clancy , Glenn Larsen , William Trepicchio , Fionula Brennan , Marc Feldmann , Brian John Foxwell , Jeffrey Feldman
- 申请人地址： GB London SW7 2AZ
- 专利权人： Wyeth and Imperial College Innovations Limited
- 当前专利权人： Wyeth and Imperial College Innovations Limited
- 当前专利权人地址： GB London SW7 2AZ
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/46
摘要：
Fusion proteins comprising a Receptor for Advanced Glycation End Products Ligand Binding Element (RAGE-LBE) and an immunoglobulin element are disclosed. Also disclosed are fusion proteins comprising a RAGE-LBE and a dimerization domain. Also disclosed are nucleic acids encoding such fusion proteins and methods for using disclosed nucleic acids and proteins to, for example, treat RAGE-related disorders. Additional compositions and methods are also disclosed.
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