- 专利标题： Antisense modulation of CD40 ligand expression
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申请号： US11039632申请日： 2005-01-20
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公开(公告)号： US20060160758A1公开(公告)日： 2006-07-20
- 发明人: C. Bennett , Susan Freier , Brenda Baker , Brett Monia , Nicholas Dean , Hong Zhang , Susan Murray , Lex Cowsert , Madeline Butler , Robert McKay , Donna Ward , William Gaarde , Ian Popoff , Jacqueline Wyatt , Andrew Watt
- 申请人： C. Bennett , Susan Freier , Brenda Baker , Brett Monia , Nicholas Dean , Hong Zhang , Susan Murray , Lex Cowsert , Madeline Butler , Robert McKay , Donna Ward , William Gaarde , Ian Popoff , Jacqueline Wyatt , Andrew Watt
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07H21/02
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of CD40 ligand. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CD40 ligand. Methods of using these compounds for modulation of CD40 ligand expression and for treatment of diseases associated with expression of CD40 ligand are provided.
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