发明申请
- 专利标题: Amino-pyridines as inhibitors of beta-secretase
- 专利标题(中): 氨基吡啶作为β-分泌酶的抑制剂
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申请号: US11344432申请日: 2006-01-31
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公开(公告)号: US20060173049A1公开(公告)日: 2006-08-03
- 发明人: Michael Malamas , William Fobare , William Solvibile , Frank Lovering , Jeffrey Condon , Albert Robichaud
- 申请人: Michael Malamas , William Fobare , William Solvibile , Frank Lovering , Jeffrey Condon , Albert Robichaud
- 申请人地址: US NJ Madison
- 专利权人: Wyeth
- 当前专利权人: Wyeth
- 当前专利权人地址: US NJ Madison
- 主分类号: C07D403/02
- IPC分类号: C07D403/02 ; A61K31/4439
摘要:
The present invention provides an amino-pyridine compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.
公开/授权文献
- US07732457B2 Amino-pyridines as inhibitors of β-secretase 公开/授权日:2010-06-08