发明申请
US20060257870A1 Cdkl 1 as modifier of branching morphogenesis and methods of use
审中-公开
Cdkl 1作为分支形态发生的调节剂和使用方法
- 专利标题: Cdkl 1 as modifier of branching morphogenesis and methods of use
- 专利标题(中): Cdkl 1作为分支形态发生的调节剂和使用方法
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申请号: US10532405申请日: 2003-10-22
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公开(公告)号: US20060257870A1公开(公告)日: 2006-11-16
- 发明人: Gregory Plowman , Felix Karim , Candace Swimmer , Hinrich Habeck , Thomas Koblizek , Stefan Schulte-Merker , Ulrike Langheinrich , Gordon Stott , Torsten Trowe , Andreas Vogel , Joerg Odenthal , Jochen Scheel , Torsten Will , Yisheng Jin , Bing Hai
- 申请人: Gregory Plowman , Felix Karim , Candace Swimmer , Hinrich Habeck , Thomas Koblizek , Stefan Schulte-Merker , Ulrike Langheinrich , Gordon Stott , Torsten Trowe , Andreas Vogel , Joerg Odenthal , Jochen Scheel , Torsten Will , Yisheng Jin , Bing Hai
- 国际申请: PCT/US03/33483 WO 20031022
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; G01N33/574 ; C12Q1/48
摘要:
Human CDKL1 genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of CDKL1 are provided.