摘要:
Human CDKL1 genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of CDKL1 are provided.
摘要:
Human MAPK7 genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MAPK7 are provided.
摘要:
Human NADK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morpho-genesis, comprising screening for agents that modulate the activity of NADK are provided.
摘要:
A computer-implemented method for using a third-party recommendation in a game system includes: receiving, at a recommendation engine and from a game system, current game context data provided in real time during a game in which at least one user participates; selecting, by the recommendation engine, at least one of multiple predefined actions based on at least the current game context data; and providing a response to the game system that identifies the selected at least one action for performance.
摘要:
A method for determining a suitability of a route including a plurality of sections for traveling on by a driver of a vehicle. The method has a step of determining a fatigue prediction value, which predicts a fatigue of the driver of the vehicle for at least one section of the route. The method also has a step of carrying out a comparison of the fatigue prediction value to a maximum fatigue value that is assigned to the at least one section of the route. Finally, the method has a step of weighting the route with a fatigue weighting that is a function of the comparison, in order to determine the suitability of the route for traveling on by the driver.
摘要:
In an embodiment, a method is provided for transmitting data. In this method, a number from a sequence of numbers is identified, and each number from the sequence is associated with a time interval. A random number is generated and it is compared with the identified number. In reference to the time interval associated with the identified number, transmission of the data to the electronic device is initiated based on the comparison.
摘要:
A method for demand charge management at public charging stations may be provided. The method may comprise collecting information related to electric vehicle (EV) charging from a plurality of interested parties by an infrastructure service cloud, computing charge rate offers based on the collected information by the infrastructure service cloud, transmitting the computed charge rate offers to a driver of an EV by the infrastructure service cloud, and reserving a charge spot for the driver using the infrastructure service when the driver accepts an offer.
摘要:
The invention relates to a nitrilase having improved activity in the reaction of a nitrile to form the corresponding carboxylic acid, in particular with respect to reacting 2-methylglutaronitrile, 1-(cyanomethyl)cyclohexane-1-carbonitrile, and benzonitrile. The nitrilase according to the invention is related to nitrilase from acidovorax facilis.
摘要:
A sheet metal component that is bent from a sheet metal blank includes at least one three-sided corner. Two edges of the three-sided corner are formed by a first bending member of the sheet metal blank bent about a first inner bending radius Ri,1 and a second bending member of the sheet metal blank bent about a second inner bending radius Ri,2, and the third edge of the three-sided corner is formed by a first blank edge of the first bending member and a second blank edge of the second bending member. The sheet metal blank has an internal corner that forms the first blank edge, the second blank edge, and a wedge-like recess that opens in the internal corner.
摘要:
In an embodiment, a method is provided for transmitting data. In this method, a number from a sequence of numbers is identified, and each number from the sequence is associated with a time interval. A random number is generated and it is compared with the identified number. In reference to the time interval associated with the identified number, transmission of the data to the electronic device is initiated based on the comparison.