- 专利标题: Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
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申请号: US11396079申请日: 2006-03-31
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公开(公告)号: US20070054925A1公开(公告)日: 2007-03-08
- 发明人: Timothy Guzi , Kamil Paruch , Michael Dwyer , Ronald Doll , Viyyoor Girijavallabhan , Alan Mallams , Carmen Alvarez , Kartik Keertikar , Jocelyn Rivera , Tin-Yau Chan , Vincent Madison , Thierry Fischmann , Lawrence Dillard , Vinh Tran , Zhen He , Ray James , Haengsoon Park , Vidyadhar Paradkar , Douglas Hobbs
- 申请人: Timothy Guzi , Kamil Paruch , Michael Dwyer , Ronald Doll , Viyyoor Girijavallabhan , Alan Mallams , Carmen Alvarez , Kartik Keertikar , Jocelyn Rivera , Tin-Yau Chan , Vincent Madison , Thierry Fischmann , Lawrence Dillard , Vinh Tran , Zhen He , Ray James , Haengsoon Park , Vidyadhar Paradkar , Douglas Hobbs
- 专利权人: Schering Corporation,Pharmacopeia, Inc.
- 当前专利权人: Schering Corporation,Pharmacopeia, Inc.
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; C07D487/04
摘要:
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.