发明申请
- 专利标题: Chemokine receptor binding compounds
- 专利标题(中): 趋化因子受体结合化合物
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申请号: US11505669申请日: 2006-08-16
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公开(公告)号: US20070066624A1公开(公告)日: 2007-03-22
- 发明人: Yuanxi Zhou , Elyse Bourque , Yongbao Zhu , Ernest McEachern , Curtis Harwig , Renato Skerlj , Gary Bridger , Tong-Shuang Li , Markus Metz
- 申请人: Yuanxi Zhou , Elyse Bourque , Yongbao Zhu , Ernest McEachern , Curtis Harwig , Renato Skerlj , Gary Bridger , Tong-Shuang Li , Markus Metz
- 申请人地址: CA Langley
- 专利权人: AnorMED, Inc.
- 当前专利权人: AnorMED, Inc.
- 当前专利权人地址: CA Langley
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; A61K31/454 ; C07D403/14 ; C07D403/04
摘要:
The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR4 or CCR5. In one aspect, these compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).