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1.发明申请公开(公告)号：US20090281308A1
公开(公告)日：2009-11-12
申请号：US12467006
申请日：2009-05-15
Applicant: Gary J. BRIDGER , Ernest J. MCEACHERN , Renato SKERLJ , Dominique SCHOLS , Ian BAIRD , Al KALLER , Curtis HARWIG , Yongbao ZHU , Gang CHEN , Krystyna SKUPINSKA , Markus METZ
Inventor： Gary J. BRIDGER , Ernest J. MCEACHERN , Renato SKERLJ , Dominique SCHOLS , Ian BAIRD , Al KALLER , Curtis HARWIG , Yongbao ZHU , Gang CHEN , Krystyna SKUPINSKA , Markus METZ
IPC: C07D401/14 , C07D409/14 , C07D417/04 , C07D413/14
CPC classification number: C07D401/14 , C07D409/14 , C07D413/14 , C07D417/14
Abstract: Compounds that interact with the CXCR4 receptor are described. These compounds are useful in treating, for Example, HIV infection and inflammatory conditions such as rheumatoid arthritis, as well as asthma or cancer, and are useful in methods to elevate progenitor and stem cell counts as well as methods to elevate white blood cell counts.
Abstract translation: 描述了与CXCR4受体相互作用的化合物。 这些化合物可用于治疗例如HIV感染和炎性病症如类风湿性关节炎以及哮喘或癌症，并且可用于提高祖细胞和干细胞计数的方法以及升高白细胞计数的方法。
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公开(公告)号：US20080087362A1
公开(公告)日：2008-04-17
申请号：US11569157
申请日：2005-07-08
Applicant: Markus Metz
Inventor： Markus Metz
IPC: B60C13/02
CPC classification number: B60C13/001
Abstract: Vehicle pneumatic tire includes a carcass having sidewalls and a tread rubber. A sidewall area is covered on an outside by a sidewall rubber strip. A moiré pattern is arranged on the sidewall rubber strip and is formed by a superimposition of at least two linear non-identical families of curves. A first family of curves of the at least two linear non-identical families of curves is formed by undulatory curves having regular wave form. A second family of curves of the at least two linear non-identical families of curves is formed by undulatory curves having irregular wave form. This abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.
Abstract translation: 车辆充气轮胎包括具有侧壁和胎面橡胶的胎体。 侧壁区域被侧壁橡胶条覆盖在外部。 在侧壁橡胶条上布置有莫尔图案，并且通过至少两个线性不相同的曲线族的叠加形成。 至少两个线性不相同的曲线族的第一族曲线由具有规则波形的波形曲线形成。 至少两个线性不相同的曲线族的第二族曲线由具有不规则波形的波形曲线形成。 该摘要并不旨在限定说明书中公开的发明，也不旨在以任何方式限制本发明的范围。
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公开(公告)号：US20050277668A1
公开(公告)日：2005-12-15
申请号：US11152589
申请日：2005-06-14
Applicant: Yuanxi Zhou , Gary Bridger , Renato Skerlj , David Bogucki , Wen Yang , Elyse Bourque , Jonathan Langille , Tong-Shuang Li , Markus Metz
Inventor： Yuanxi Zhou , Gary Bridger , Renato Skerlj , David Bogucki , Wen Yang , Elyse Bourque , Jonathan Langille , Tong-Shuang Li , Markus Metz
IPC: A61K31/4545 , C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14 , C12N20060101 , C07D41/14
CPC classification number: C07D417/14 , C07D401/12 , C07D401/14 , C07D413/14
Abstract: The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. These compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).
Abstract translation: 本发明涉及趋化因子受体结合化合物，药物组合物及其用途。 更具体地，本发明涉及趋化因子受体活性的调节剂，优选CCR5的调节剂。 这些化合物表现出对人体免疫缺陷病毒（HIV）感染靶细胞的保护作用。
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公开(公告)号：US20100298366A1
公开(公告)日：2010-11-25
申请号：US12851495
申请日：2010-08-05
Applicant: Yuanxi ZHOU , Elyse Bourque , Yongbao Zhu , Jonathan Langille , Markus Metz , Wen Yang , Ernest J. Mceachern , Curtis Harwig , Ian R. Baird , Tong-Shuang Li , Renato T. Skerlj
Inventor： Yuanxi ZHOU , Elyse Bourque , Yongbao Zhu , Jonathan Langille , Markus Metz , Wen Yang , Ernest J. Mceachern , Curtis Harwig , Ian R. Baird , Tong-Shuang Li , Renato T. Skerlj
IPC: A61K31/4545 , C07D413/14 , C07D413/04 , C07D401/14 , A61K31/454 , A61K31/506 , A61P31/18
CPC classification number: C07D413/14 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/14
Abstract: The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. These compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).
Abstract translation: 本发明涉及趋化因子受体结合化合物，药物组合物及其用途。 更具体地，本发明涉及趋化因子受体活性的调节剂，优选CCR5的调节剂。 这些化合物表现出对人体免疫缺陷病毒（HIV）感染靶细胞的保护作用。
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公开(公告)号：USD624007S1
公开(公告)日：2010-09-21
申请号：US29287301
申请日：2007-07-20
Applicant: Markus Metz
Designer： Markus Metz
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Patent Agency Ranking
公开(公告)号：US20090099205A1
公开(公告)日：2009-04-16
申请号：US11453221
申请日：2006-06-14
Applicant: Yuanxi Zhou , Elyse Bourque , Yongbao Zhu , Jonathan Langille , Markus Metz , Wen Yang , Ernest J. McEachern , Curtis Harwig , Ian R. Baird , Tong-Shuang Li , Renato T. Skerlj
Inventor： Yuanxi Zhou , Elyse Bourque , Yongbao Zhu , Jonathan Langille , Markus Metz , Wen Yang , Ernest J. McEachern , Curtis Harwig , Ian R. Baird , Tong-Shuang Li , Renato T. Skerlj
IPC: A61K31/506 , C07D403/12 , A61K31/4545 , C07D409/14 , C12N5/06
CPC classification number: C07D413/14 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/14
Abstract: The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. These compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).
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公开(公告)号：US20050217775A1
公开(公告)日：2005-10-06
申请号：US11088751
申请日：2005-03-25
Applicant: Markus Metz
Inventor： Markus Metz
CPC classification number: B60C11/13 , B60C11/11 , B60C11/1323
Abstract: A tire includes a tread rubber having a positive profile formed by at least one circumferential groove. Wherein the transverse grooves extends into the positive profile from the circumferential groove to form block flank surfaces. Further, the transverse grooves have bending points at which a change of direction takes place at an obtuse angle. Further still, at least one block flank has at least three flank surfaces, wherein at least one of the flank surfaces is inclined and connected to an upper surface of the positive profile. The tire is a vehicle pneumatic tire. The instant abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.
Abstract translation: 轮胎包括具有由至少一个周向槽形成的正轮廓的胎面橡胶。 其中横向槽从周向槽延伸到正轮廓以形成块侧面。 此外，横向槽具有以钝角发生方向变化的弯曲点。 此外，至少一个块侧面具有至少三个侧面，其中，所述侧面中的至少一个倾斜并连接到所述正轮廓的上表面。 轮胎是车辆充气轮胎。 本摘要既不旨在限定本说明书中公开的发明，也不旨在以任何方式限制本发明的范围。
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公开(公告)号：USD472559S1
公开(公告)日：2003-04-01
申请号：US29147647
申请日：2001-09-04
Applicant: Markus Metz
Designer： Markus Metz
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9.发明授权Methods, apparatuses, systems and computer readable mediums to create documents and templates using domain ontology concepts 有权使用领域本体概念创建文档和模板的方法，设备，系统和计算机可读介质公开(公告)号：US09411799B2
公开(公告)日：2016-08-09
申请号：US13440569
申请日：2012-04-05
Applicant: Andrew John Hewett , Martin Huber , Gerhard Kohl , Markus Metz , James Pressler , Michael Rusitska
Inventor： Andrew John Hewett , Martin Huber , Gerhard Kohl , Markus Metz , James Pressler , Michael Rusitska
CPC classification number: G06F17/248
Abstract: A document and template creation system includes a document and template creation device. The document and template creation device is configured to identify at least one domain ontology concept based on at least a portion of a text-string input into a document, propose the at least one domain ontology concept for selection by the user, and insert at least one of the at least one domain ontology concept into the document in response to selection by the user.
Abstract translation: 文档和模板创建系统包括文档和模板创建设备。 文档和模板创建设备被配置为基于输入到文档中的文本串的至少一部分来识别至少一个域本体概念，提出至少一个领域本体概念供用户选择，并且至少插入 将至少一个领域本体概念中的一个引入文档以响应于用户的选择。
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10.发明申请METHODS, APPARATUSES, SYSTEMS AND COMPUTER READABLE MEDIUMS TO CREATE DOCUMENTS AND TEMPLATES 有权方法，设备，系统和计算机可读介质创建文档和模板公开(公告)号：US20130268852A1
公开(公告)日：2013-10-10
申请号：US13440569
申请日：2012-04-05
Applicant: Andrew John Hewett , Martin Huber , Gerhard Kohl , Markus Metz , James Pressler , Michael Rusitska
Inventor： Andrew John Hewett , Martin Huber , Gerhard Kohl , Markus Metz , James Pressler , Michael Rusitska
IPC: G06F17/21
CPC classification number: G06F17/248
Abstract: A document and template creation system includes a document and template creation device. The document and template creation device is configured to identify at least one domain ontology concept based on at least a portion of a text-string input into a document, propose the at least one domain ontology concept for selection by the user, and insert at least one of the at least one domain ontology concept into the document in response to selection by the user.
Abstract translation: 文档和模板创建系统包括文档和模板创建设备。 文档和模板创建设备被配置为基于输入到文档中的文本串的至少一部分来识别至少一个域本体概念，提出至少一个领域本体概念供用户选择，并且至少插入 将至少一个领域本体概念中的一个引入文档以响应于用户的选择。
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