发明申请
US20070128194A1 Preparation of monoclonal antibody to N-myc downstream regulated gene 2 and determination of NDRG2 using protein chip
有权
制备N-myc下游调控基因2的单克隆抗体，并使用蛋白芯片测定NDRG2
- 专利标题： Preparation of monoclonal antibody to N-myc downstream regulated gene 2 and determination of NDRG2 using protein chip
- 专利标题（中）： 制备N-myc下游调控基因2的单克隆抗体，并使用蛋白芯片测定NDRG2
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申请号： US11393897申请日： 2006-03-31
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公开(公告)号： US20070128194A1公开(公告)日： 2007-06-07
- 发明人: Eun Song , Jae Kim , Hee Lee , Jong Lim , Seung Choi , Mi Cho , Kyoung Baek , Jin Kim , Jong Kim , Do Yoon , Dur Kwon , Mi-Young Park , Young Yeom , Yong-Kyung Choe , Young-Jun Kim
- 申请人： Eun Song , Jae Kim , Hee Lee , Jong Lim , Seung Choi , Mi Cho , Kyoung Baek , Jin Kim , Jong Kim , Do Yoon , Dur Kwon , Mi-Young Park , Young Yeom , Yong-Kyung Choe , Young-Jun Kim
- 申请人地址： KR Daejeon
- 专利权人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
- 当前专利权人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
- 当前专利权人地址： KR Daejeon
- 优先权： KR2005-0118140 20051206
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; G01N33/567 ; C12N5/06 ; C07K16/40
摘要：
The present invention relates to a monoclonal antibody specific for N-myc downstream regulated gene 2 (NDRG 2) protein, a cell line producing the monoclonal antibody, a method for measuring a quantity and quality of NDRG 2 protein, and a protein chip using the same. In the present invention, NDRG 2, a cancer-related factor is specifically expressed in dendritic cells differentiated from a monocyte of human peripheral blood. Accordingly, the monoclonal antibody specific for the NDRG 2 protein, the protein chip comprising the same and the method for measuring a quantity and quality of the NDRG 2 protein by using the same can be applied to elucidate characteristics of the dendritic cell and perform a research on the NDRG 2. Therefore, the present invention may help clinically to investigate and treat intractable diseases and cancers using the dendritic cell.
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