发明申请
- 专利标题： Pyrrolopyridine kinase inhibiting compounds
- 专利标题（中）： 吡咯并吡啶激酶抑制化合物
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申请号： US11634003申请日： 2006-12-05
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公开(公告)号： US20070129364A1公开(公告)日： 2007-06-07
- 发明人: Han-Qing Dong , Kenneth Foreman , An-Hu Li , Mark Mulvihill , Bijoy Panicker , Arno Steinig , Kathryn Stolz , Qinghua Weng , Meizhong Jin , Brian Volk , Jing Wang , Ti Wang , James Beard
- 申请人： Han-Qing Dong , Kenneth Foreman , An-Hu Li , Mark Mulvihill , Bijoy Panicker , Arno Steinig , Kathryn Stolz , Qinghua Weng , Meizhong Jin , Brian Volk , Jing Wang , Ti Wang , James Beard
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/496 ; A61K31/4745 ; C07D471/02
摘要：
Compounds represented by Formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, are inhibitors of least one of the Abl, Aurora-A, Blk, c-Raf, cSRC, Src, PRK2, FGFR3, Flt3, Lck, Mek1, PDK-1, GSK3β, EGFR, p70S6K, BMX, SGK, CaMKII, Tie-2, IGF-1R, Ron, Met, and KDR kinases in animals, including humans, for the treatment and/or prevention of various diseases and conditions such as cancer.