发明申请
- 专利标题： Fusion Proteins
- 专利标题（中）： 融合蛋白
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申请号： US10558862申请日： 2004-06-10
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公开(公告)号： US20070253966A1公开(公告)日： 2007-11-01
- 发明人: Wolfgang Glaesner , Rohn Millican Jr , Yu Tian , Sheng-Hung Tschang , Andrew Vick
- 申请人： Wolfgang Glaesner , Rohn Millican Jr , Yu Tian , Sheng-Hung Tschang , Andrew Vick
- 申请人地址： US IN Indianapolis
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： US IN Indianapolis
- 国际申请： PCT/US04/16611 WO 20040610
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07H21/04 ; C12P21/04 ; C12N5/06 ; C07K16/46
摘要：
The invention provides active therapeutic peptides fused to specific IgG4-Fc derivatives. These fusion proteins have an increased half-life, reduced half antibody formation, and reduced effector activity, while not being immnunogenic. The fusion proteins are useful in treating human diseases as well as a variety of other conditions or disorders.
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