Invention Application
- Patent Title: SPIROCYCLIC HETEROCYCLIC DERIVATIVES AND METHODS OF THEIR USE
- Patent Title (中): 螺环杂环衍生物及其使用方法
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Application No.: US11696585Application Date: 2007-04-04
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Publication No.: US20070269374A1Publication Date: 2007-11-22
- Inventor: Roland Dolle , Bertrand Le Bourdonnec , Guo-Hua Chu
- Applicant: Roland Dolle , Bertrand Le Bourdonnec , Guo-Hua Chu
- Main IPC: A61K31/438
- IPC: A61K31/438 ; A61K31/015 ; A61K31/135 ; A61K31/33 ; A61K31/4523 ; A61K31/4748 ; A61K31/5375 ; A61K51/04 ; A61P15/00 ; A61P29/00 ; A61P25/36 ; A61P25/34 ; A61P25/32 ; A61P25/24 ; A61P25/22 ; A61P25/16 ; A61P25/14 ; A61P25/00 ; C07D401/04 ; A61P9/12 ; A61P9/10 ; A61P9/00 ; A61P37/00 ; A61P11/06 ; A61K31/5377 ; A61K31/485 ; A61K31/4545 ; A61K31/445 ; A61K31/381 ; A61K31/4166

Abstract:
Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the δ-opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other δ-opioid receptor-mediated diseases, disorders, and/or conditions.
Public/Granted literature
- US07576207B2 Spirocyclic heterocyclic derivatives and methods of their use Public/Granted day:2009-08-18
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