发明申请
- 专利标题： BIOSENSOR ELECTRODE MEDIATORS FOR REGENERATION OF COFACTORS
- 专利标题（中）： 生物传感器电极用于再生器的介质
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申请号： US11849790申请日： 2007-09-04
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公开(公告)号： US20070289881A1公开(公告)日： 2007-12-20
- 发明人: Nigel Forrow , Gurdial Sanghera , Jared Watkin , Stephen Walters
- 申请人： Nigel Forrow , Gurdial Sanghera , Jared Watkin , Stephen Walters
- 申请人地址： US IL Abbott Park
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： US IL Abbott Park
- 主分类号： G01N27/26
- IPC分类号： G01N27/26 ; C12M1/34
摘要：
The present invention is based on the discovery of NAD+ and NADP+ mediator compounds that do not bind irreversibly to thiol groups in the active sites of intracellular dehydrogenase enzymes. Such mediator compounds avoid a common mode of enzyme inhibition. The mediators can therefore increase the stability and reliability of the electrical response in amperometric electrodes constructed from NAD- or NADP-dependent enzymes.
公开/授权文献
- US08012341B2 Biosensor electrode mediators for regeneration of cofactors 公开/授权日：2011-09-06
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