发明申请
US20070299039A1 Substituted benz-azoles and methods of their use as inhibitors of Raf kinase
失效
取代的苯并唑及其用作Raf激酶抑制剂的方法
- 专利标题: Substituted benz-azoles and methods of their use as inhibitors of Raf kinase
- 专利标题(中): 取代的苯并唑及其用作Raf激酶抑制剂的方法
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申请号: US11282939申请日: 2005-11-18
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公开(公告)号: US20070299039A1公开(公告)日: 2007-12-27
- 发明人: Payman Amiri , Wendy Fantl , Teresa Hansen , Barry Levine , Christopher McBride , Daniel Poon , Savithri Ramurthy , Paul Renhowe , Cynthia Shafer , Sharadha Subramanian , Leonard Sung
- 申请人: Payman Amiri , Wendy Fantl , Teresa Hansen , Barry Levine , Christopher McBride , Daniel Poon , Savithri Ramurthy , Paul Renhowe , Cynthia Shafer , Sharadha Subramanian , Leonard Sung
- 申请人地址: US CA Emeryville
- 专利权人: Chiron Corporation
- 当前专利权人: Chiron Corporation
- 当前专利权人地址: US CA Emeryville
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; A61K31/444 ; A61K31/497 ; A61K31/5377 ; A61K31/55 ; A61K31/665 ; A61P35/00 ; C07D401/10 ; C07D401/14 ; C07D413/10 ; C07D413/14 ; C07D417/10
摘要:
New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
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