发明申请
- 专利标题： SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES
- 专利标题（中）： 取代的喹唑啉-4-亚胺类似物
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申请号： US11864987申请日： 2007-09-29
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公开(公告)号： US20080015183A1公开(公告)日： 2008-01-17
- 发明人: Rajagopal Bakthavatchalam , Charles Blum , Harry Brielmann , Timothy Caldwell , Stephane De Lombaert , Kevin Hodgetts , Xiaozhang Zheng , James Krause , Uri Herzberg , Taeyoung Yoon
- 申请人： Rajagopal Bakthavatchalam , Charles Blum , Harry Brielmann , Timothy Caldwell , Stephane De Lombaert , Kevin Hodgetts , Xiaozhang Zheng , James Krause , Uri Herzberg , Taeyoung Yoon
- 申请人地址： US CT Branford
- 专利权人： Neurogen Corporation
- 当前专利权人： Neurogen Corporation
- 当前专利权人地址： US CT Branford
- 主分类号： A61K31/517
- IPC分类号： A61K31/517 ; A61K31/47 ; A61K31/519 ; A61K31/541 ; A61P11/14 ; A61P17/02 ; C07D215/58 ; C07D237/30 ; C07D279/12 ; C07D471/04 ; C07D417/12 ; C07D413/14 ; C07D413/10 ; C07D401/14 ; C07D401/10 ; C07D239/84 ; C07D223/04 ; A61P25/04 ; A61P11/16 ; A61K31/55 ; A61K31/5377 ; A61K31/502
摘要：
Substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
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