发明申请
US20080019958A1 POLYNUCLEOTIDE ENCODING A NOVEL ACYL COENZYME A, MONOACYLGLYCEROL ACYLTRANSFERASE-3 (MGAT3), AND USES THEREOF
审中-公开
多核苷酸编码新型ACYL COENZYME A，单乙酰胆碱酯酶3（MGAT3）及其用途
- 专利标题： POLYNUCLEOTIDE ENCODING A NOVEL ACYL COENZYME A, MONOACYLGLYCEROL ACYLTRANSFERASE-3 (MGAT3), AND USES THEREOF
- 专利标题（中）： 多核苷酸编码新型ACYL COENZYME A，单乙酰胆碱酯酶3（MGAT3）及其用途
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申请号： US11779308申请日： 2007-07-18
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公开(公告)号： US20080019958A1公开(公告)日： 2008-01-24
- 发明人: John Feder , Thomas Nelson , Jian Chen , Rupalie Meegalla , Michael Ramaker , Dong Cheng
- 申请人： John Feder , Thomas Nelson , Jian Chen , Rupalie Meegalla , Michael Ramaker , Dong Cheng
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; A61K38/45 ; C12N1/00 ; C12P21/02 ; C12Q1/48 ; C12N9/10 ; A61P1/00
摘要：
The present invention provides novel polynucleotides encoding MGAT3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MGAT3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, such as obesity. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.