利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

119 条记录 (耗时 0.058 秒)

    Textual Content Speed Player
    1.
    发明申请
    Textual Content Speed Player 审中-公开

    公开(公告)号：US20180121053A1

    公开(公告)日：2018-05-03

    申请号：US15693278

    申请日：2017-08-31

    申请人： Andrew Thomas Nelson

    发明人： Andrew Thomas Nelson

    IPC分类号： G06F3/0481 ,  G10L13/04 ,  G06T11/60 ,  G06F17/21 ,  G06T13/80

    CPC分类号： G06F3/04812 ,  G06F3/0483 ,  G06F17/211 ,  G06F17/214 ,  G06T11/60 ,  G06T13/80 ,  G09B5/02 ,  G09B17/006 ,  G09B17/04 ,  G10L13/043

    摘要： A computer program that requires nothing more of a user than to read their choice of textual content in an animated format to increase reading speed via reconditioned reading behavior. The computer program: highlights a word on a page and puts a copy of the word in the center of the page so a reader can fix their eyes on the center of the page and still satisfy the common scanning strategy of repositioning the eyes to project a word on the center of the retina while the reader is reconditioned, by the highlighting of words progressing through the body text, to use the faster scanning strategy of fixing the eyes and changing the position on the retina being read; presents a picture representing the meaning of each word in order to recondition a user to use the faster cognitive strategy of triggering recognition of meaning with a picture; presents textual content with a timing based on syllables in order to create a presentation of textual content in sync with the natural timing of speech; can add a speaking voice to the animated format which enables the non-reader to learn printed language through context alone; can record the audio of an individual word read out loud from a selection of textual content for future playback of any textual content containing the word.

    METHOD AND APPARATUS FOR MAKING A FLUID CONNECTION TO A CONTAINER
    2.
    发明申请
    METHOD AND APPARATUS FOR MAKING A FLUID CONNECTION TO A CONTAINER 审中-公开
    用于制造与集装箱的流体连接的方法和装置

    公开(公告)号：US20100156090A1

    公开(公告)日：2010-06-24

    申请号：US12601061

    申请日：2008-05-23

    申请人： Thomas Nelson O'Connor

    发明人： Thomas Nelson O'Connor

    IPC分类号： F16L35/00

    CPC分类号： F16L41/086 ,  F16L23/18

    摘要： A method and apparatus for connecting a container (102) to a fluid conduit (108), including a container (102) having an interior and an exterior and a receptacle (104) with an opening and an exterior sealing surface adjoining and surrounding the opening, a fluid conduit (108) having at one end a collar (304), either affixed to or separate from the conduit (108), the collar (304) affixed to the receptacle (104) with a seal (106) placed between the receptacle (104) and the fluid conduit (108).

    摘要翻译： 一种用于将容器（102）连接到流体导管（108）的方法和装置，包括具有内部和外部的容器（102）和具有开口的容器（104），以及邻接并围绕开口的外部密封表面 ，一个流体导管（108），其一端具有固定到导管（108）上或与导管（108）分离的套环（304），该套环（304）用一个密封件（106）固定在容器（104）上， 容器（104）和流体导管（108）。

    Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier
    3.
    发明授权
    Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier 有权
    用于运输物质穿过血脑屏障的人造低密度脂蛋白载体

    公开(公告)号：US07682627B2

    公开(公告)日：2010-03-23

    申请号：US11648808

    申请日：2007-01-03

    申请人： Thomas Nelson ,  Alessandro Quattrone ,  Daniel Alkon

    发明人： Thomas Nelson ,  Alessandro Quattrone ,  Daniel Alkon

    IPC分类号： A61K38/00 ,  A61K31/58 ,  A61K39/395 ,  A61K39/00 ,  A61K9/127 ,  A61K9/50

    CPC分类号： A61K9/127 ,  A61K9/1275 ,  A61K31/704 ,  Y10S977/906

    摘要： This invention relates to a highly efficient artificial low-density lipoprotein (LDL) carrier system for the targeted delivery therapeutic agents across the blood-brain barrier (BBB). In particular, this invention relates to artificial LDL particles comprised of three lipid elements: phosphatidyl choline, fatty-acyl-cholesterol esters, and at least one apolipoprotein. The present invention further relates to compositions, methods and kits comprising artificial LDL particles for targeting drugs to and across the BBB for the prevention and treatment of brain diseases.

    摘要翻译： 本发明涉及穿过血脑屏障（BBB）的靶向递送治疗剂的高效人造低密度脂蛋白（LDL）载体系统。 特别地，本发明涉及由三种脂质元素组成的人造LDL颗粒：磷脂酰胆碱，脂肪酰基胆固醇酯和至少一种载脂蛋白。 本发明进一步涉及包含人造LDL颗粒的组合物，方法和试剂盒，用于将药物靶向和穿过BBB以预防和治疗脑部疾病。

    ELECTRICAL TESTING DEVICE
    4.
    发明申请
    ELECTRICAL TESTING DEVICE 有权
    电气测试设备

    公开(公告)号：US20090045817A1

    公开(公告)日：2009-02-19

    申请号：US12019326

    申请日：2008-01-24

    申请人： Gerald R. Savicki, JR. ,  Thomas Nelson Packard ,  Dejan Radosavljevic

    发明人： Gerald R. Savicki, JR. ,  Thomas Nelson Packard ,  Dejan Radosavljevic

    IPC分类号： G01R31/28

    CPC分类号： H01R25/003

    摘要： The present invention is directed to an electrical testing device for use in an AC electrical power distribution circuit including a plurality of AC electric power transmitting wires coupled between an AC power distribution point and a device box. The device includes a plurality of electrical probes configured for insertion into an outlet receptacle. A plug test connection arrangement is configured to receive a plug connector when inserted therein. The plug connector includes a plurality of plug contacts and a termination arrangement configured to terminate the plurality of AC electric power transmitting wires such that electrical continuity is established between the AC power distribution point and the plurality of plug contacts. The plug test connection arrangement includes a plurality of test contacts configured to mate with the plurality of plug contacts when the plug connector is inserted into the plug test connection arrangement. The termination arrangement being in a detached relationship from the device box after the plurality of AC electric power transmitting wires are terminated. An electrical test circuit is configured to perform at least one electrical test. The electrical test circuit includes a switch mechanism configured to connect the electrical test circuit to the plurality of electrical probes at a first switch setting or connect the electrical test circuit to the plurality of test contacts at a second switch setting. At least one shock mitigation structure is coupled to the plurality of electrical probes or the plug test connection arrangement and is configured to prevent user access to the plurality of electrical probes or the plug test connection arrangement.

    摘要翻译： 本发明涉及一种用于交流配电电路的电气测试装置，该电气配电电路包括耦合在交流配电点与装置盒之间的多个交流电力传输线。 该装置包括构造成用于插入出口插座的多个电探头。 插头测试连接装置被配置为在插入插头连接器时插入插头连接器。 插头连接器包括多个插头触点和终端装置，其被配置为终止多个AC电力传输线，使得在AC配电点和多个插头触点之间建立电连接。 插头测试连接装置包括多个测试触点，其被配置为当插头连接器插入插头测试连接装置时与多个插头触头配合。 在多个AC电力传输线终止之后，终端装置处于与装置箱分离的关系。 电测试电路被配置为执行至少一个电测试。 电测试电路包括开关机构，其被配置为在第一开关设置下将电测试电路连接到多个电探针，或者在第二开关设置下将电测试电路连接到多个测试触点。 至少一个减震结构耦合到多个电探针或插头测试连接装置，并且被配置为防止用户访问多个电探针或插头测试连接装置。

    Combined machine identification and diagnosis device
    7.
    发明申请
    Combined machine identification and diagnosis device 审中-公开
    机组识别与诊断装置

    公开(公告)号：US20070199989A1

    公开(公告)日：2007-08-30

    申请号：US11363339

    申请日：2006-02-27

    申请人： Richard Piety ,  Thomas Nelson

    发明人： Richard Piety ,  Thomas Nelson

    IPC分类号： G06K7/00 ,  G06K7/08

    CPC分类号： G06K19/07749 ,  G06K19/0716

    摘要： An apparatus that combines an RFID-like machine configuration reader with a device for acquiring machine diagnostic information. The apparatus includes an RFID-like communicator with an antenna and a machine diagnostic sensor, with the RFID-like communicator and the machine diagnostic sensor being substantially combined in a single housing. The apparatus is generally used with a portable data processor. The machine diagnostic sensor may be a thermal sensor, a vibration sensor, a flux sensor, or any other diagnostic sensor used in analysis of machine health. Electromagnetic interference shielding material may be disposed between the RFID-like communicator antenna and the machine diagnostic sensor to prevent electromagnetic interference between the RFID-like communicator and the machine diagnostic sensor. A method of diagnosing the condition of a machine using a combined RFID-like machine configuration communicator and machine diagnostic sensor is provided where the machine has an RFID-like transponder tag and an inspection point. The combined diagnostic reader is positioned in a first orientation where the RFID-like machine configuration communicator is in operative communication with the RFID-like transponder tag to read machine configuration date, and then the diagnostic reader is positioned in a second orientation where the machine diagnostic sensor is proximate to the inspection point to acquire machine diagnostic information.

    摘要翻译： 一种将RFID类机器配置读取器与用于获取机器诊断信息的装置组合的装置。 该装置包括具有天线和机器诊断传感器的类RFID通信器，RFID样通信器和机器诊断传感器基本上组合在单个外壳中。 该装置通常与便携式数据处理器一起使用。 机器诊断传感器可以是用于分析机器健康的热传感器，振动传感器，通量传感器或任何其它诊断传感器。 电磁干扰屏蔽材料可以设置在RFID状通信天线和机器诊断传感器之间，以防止RFID状通信器与机器诊断传感器之间的电磁干扰。 提供了一种使用组合的RFID类机器配置通信器和机器诊断传感器来诊断机器的状况的方法，其中机器具有RFID样应答器标签和检查点。 组合的诊断读取器位于第一方向，其中类RFID机器配置通信器与RFID状态的应答器标签操作性地通信以读取机器配置日期，然后将诊断读取器定位在第二方向，其中机器诊断 传感器靠近检查点以获取机器诊断信息。

    Polynucleotide encoding a novel human serpin secreted from lymphoid cells, LSI-01
    9.
    发明授权
    Polynucleotide encoding a novel human serpin secreted from lymphoid cells, LSI-01 有权
    编码从淋巴细胞分泌的新型人丝氨酸蛋白酶的多核苷酸，LSI-01

    公开(公告)号：US07256267B2

    公开(公告)日：2007-08-14

    申请号：US11329900

    申请日：2006-01-11

    申请人： Jian Chen ,  Thomas Nelson ,  Donna A Bassolino ,  Daniel L. Cheney

    发明人： Jian Chen ,  Thomas Nelson ,  Donna A Bassolino ,  Daniel L. Cheney

    IPC分类号： C07K14/81 ,  C07K19/00 ,  C12N15/15 ,  C12N15/62 ,  C12N15/79

    CPC分类号： C07K14/8121 ,  A61K38/00 ,  C07K2299/00

    摘要： The present invention provides novel polynucleotides encoding LSI-01 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LSI-01 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码LSI-01多肽的新型多核苷酸，其片段和同系物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型LSI-01多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。