发明申请
- 专利标题: COMPOUNDS THAT INHIBIT TRPV1 AND USES THEREOF
- 专利标题(中): 禁止TRPV1的化合物及其用途
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申请号: US11844712申请日: 2007-08-24
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公开(公告)号: US20080058401A1公开(公告)日: 2008-03-06
- 发明人: Chih-hung Lee , Richard Perner , Brian Brown , John Darbyshire
- 申请人: Chih-hung Lee , Richard Perner , Brian Brown , John Darbyshire
- 申请人地址: US IL Abbott Park
- 专利权人: Abbott Laboratories
- 当前专利权人: Abbott Laboratories
- 当前专利权人地址: US IL Abbott Park
- 主分类号: A61K31/416
- IPC分类号: A61K31/416 ; A61P29/00 ; C07D231/56
摘要:
Compounds of formula (I) wherein R3, R7, R9 and L are defined in the description are TRPV1 antagonists that exhibit low inhibitory activity against CYP3A4. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
公开/授权文献
- US07767705B2 Compounds that inhibit TRPV1 and uses thereof 公开/授权日:2010-08-03
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