发明申请
- 专利标题： C-Kit Modulators And Methods Of Use
- 专利标题（中）： C-Kit调制器和使用方法
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申请号： US10569873申请日： 2004-08-27
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公开(公告)号： US20080096892A1公开(公告)日： 2008-04-24
- 发明人: Wei Cheng , Erick Wang Co , Moon Hwan Kim , Rhett Ronald Klein , Donna T. Le , Amy Lew Tsuhako , John M. Nuss , Wei Xu , William Bajjalieh
- 申请人： Wei Cheng , Erick Wang Co , Moon Hwan Kim , Rhett Ronald Klein , Donna T. Le , Amy Lew Tsuhako , John M. Nuss , Wei Xu , William Bajjalieh
- 申请人地址： US CA South San Francisco
- 专利权人： Exelixis, Inc.
- 当前专利权人： Exelixis, Inc.
- 当前专利权人地址： US CA South San Francisco
- 国际申请： PCT/US04/28001 WO 20040827
- 主分类号： A61K31/498
- IPC分类号： A61K31/498 ; C07D257/04 ; A61K31/41 ; C07D249/06 ; A61K31/4192 ; C07C233/15 ; A61K31/505 ; A61K31/4406 ; C12N5/06 ; C12Q1/48 ; G01N33/566 ; C07D213/30 ; C07D239/26 ; A61K31/167 ; C07D249/08 ; A61K31/4196 ; C07D241/42
摘要：
The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellu-lar activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Even more specifically, the invention provides compounds for modulating c-Kit kinase activity and methods of treating diseases mediated by c-Kit activity utilizing the compounds and pharmaceutical compositions thereof.
公开/授权文献
- US08362017B2 C-kit modulators and methods of use 公开/授权日：2013-01-29
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